Are containment safety transfer devices (CSTDs) required for administering hazardous drugs (HDs)?

The requirement for containment safety transfer devices (CSTDs) in the administration of hazardous drugs (HDs) is based on the need to minimize the risk of exposure to these drugs, which can be detrimental to healthcare workers and patients. The correct answer indicates that CSTDs are necessary when the dosage form permits their use and no other safety controls are in place.

This aligns with USP <800> guidelines, which emphasize that health care facilities must utilize appropriate safety measures when handling HDs to prevent drug exposure through inhalation, ingestion, or dermal absorption. CSTDs play a critical role in providing a barrier against environmental contamination and minimizing the risk of exposure during the transfer of these dangerous compounds.

Moreover, the guidelines recognize that there may be scenarios where CSTDs may not be feasible for certain dosage forms, such as those that cannot be manipulated safely within a CSTD. In such instances, other forms of engineering controls must be implemented to ensure safety, supporting the rationale behind the answer being correct. Therefore, understanding the context of when and how CSTDs are used reflects adherence to safety protocols when engaging with hazardous drugs.