Can the C-PEC be the sole source of external venting for the C-SEC?

The correct answer is that the C-PEC (Compounding Primary Engineering Control) can account for 100% of external venting. This is based on the guidelines set forth in USP <800>, which ensures proper ventilation and containment of hazardous drugs during compounding processes.

The C-PEC is designed to provide an environment that minimizes the exposure of workers and the environment to hazardous drugs. When properly designed and maintained, a C-PEC that includes appropriate external venting can efficiently handle ventilation needs without necessitating additional venting strategies. This means that, as long as the C-PEC is equipped with an adequate external venting system, it can fully satisfy the requirements for air management and ensure that hazardous contaminants do not escape into the surrounding areas.

Considerations are made in terms of the system’s efficiency, proper installation, and routine testing and maintenance to ensure that it continues to perform adequately. Therefore, if a C-PEC is designed to fully manage air flow and venting effectively, it can indeed serve as the sole source of external venting for the C-SEC (Compounding Secondary Engineering Control), thereby making this position valid and in accordance with regulatory standards.