What action is taken if contamination is found during environmental wipe sampling?

When contamination is identified during environmental wipe sampling, the appropriate action is to identify, document, and contain the cause of contamination. This approach is crucial because it ensures that the source of the contamination is understood and addressed, preventing further issues and ensuring a safe working environment.

By identifying the specific contaminant and documenting the circumstances surrounding the finding, the facility can develop strategies to mitigate the risk of future contamination. Additionally, containing the contamination limits its spread and protects both the product and personnel involved in handling hazardous materials. This systematic response aligns with the best practices outlined in USP <800>, which emphasizes the importance of maintaining a safe environment when working with hazardous drugs.

Other choices, while they might seem relevant, do not provide the same level of proactive handling needed in such a situation. Ignoring results would lead to continued contamination risks, training all staff immediately without a clear cause might cause unnecessary panic or create confusion, and notifying regulatory authorities may not be necessary unless there is a significant health threat. Therefore, option C is the most effective and responsible course of action.