What is an important aspect of engineering controls when handling hazardous drugs?

The use of Class II biological safety cabinets (BSCs) or compounding aseptic containment isolators is a critical component of engineering controls when handling hazardous drugs. These devices are designed to provide a sterile environment and to protect both the personnel and the environment from the potential exposure to hazardous substances.

Class II BSCs are specifically designed to maintain both product protection and worker safety by providing a filtered airflow that helps prevent the escape of contaminants. They are equipped with HEPA filters that effectively capture hazardous aerosols generated during the handling and compounding of these drugs. Compounding aseptic containment isolators also provide a controlled environment that further enhances safety, reducing the risk of exposure during the preparation and manipulation of hazardous drugs.

In contrast, options such as open shelf storage, reliance solely on personal protective equipment, and allowing unrestricted airflow do not provide adequate safety measures against exposure to hazardous drugs. Open shelf storage lacks the necessary containment and environmental controls, personal protective equipment alone is not sufficient to prevent exposure or ensure safety without proper engineering controls, and unrestricted airflow can facilitate the spread of contaminants. Thus, utilizing BSCs or isolators is essential for compliance with safety standards and guidelines governing the handling of hazardous drugs.