What is an important feature of a primary engineering control (PEC) for hazardous drugs?

A primary engineering control (PEC) is essential in the handling of hazardous drugs to protect the environment and ensure the safety of pharmacy personnel. The provision of an ISO Class 5 environment is a critical feature of a PEC because it directly relates to the control of airborne contaminants during the compounding of sterile products, particularly those that involve hazardous drugs.

An ISO Class 5 environment indicates that the airborne particle count is kept to a minimum, thereby reducing the risk of contamination. This level of control is paramount when working with hazardous drugs, which can pose serious health risks if they become contaminated or if the environment is not sufficiently controlled. The PEC, such as a Class II biological safety cabinet or a compounding aseptic isolator, is designed to maintain these stringent cleanliness levels. Therefore, ensuring that the PEC provides an ISO Class 5 environment is vital for compliance with safety standards and for the protection of both patients and healthcare workers.