What is the purpose of monitoring negative pressure storage areas and nonsterile compounding areas with a pressure gauge?

Monitoring negative pressure storage areas and nonsterile compounding areas with a pressure gauge primarily serves to maintain pressure requirements continually. In facilities handling hazardous drugs, negative pressure is essential to ensure that any airborne contaminants, including those released from the handling of these substances, are contained within the designated area and do not escape into surrounding spaces.

By maintaining appropriate negative pressure, the facility can effectively protect patients, staff, and the environment from the potential risks associated with exposure to hazardous drugs. This continuous monitoring helps ensure compliance with safety standards, such as those outlined in USP <800>, which sets guidelines for the safe handling of hazardous drugs. Maintaining the correct pressure levels is critical in achieving these safety and efficacy standards in compounding and storage areas.