What must be done with PPE used during the handling of hazardous drugs?

Personal Protective Equipment (PPE) used during the handling of hazardous drugs is classified as potentially contaminated and must be managed with care to prevent exposure to hazardous substances. The correct answer emphasizes that PPE must be discarded in clearly labeled hazardous waste containers, which ensures that it is treated as hazardous waste and handled in accordance with regulations that protect workers and the environment.

When PPE is worn while handling hazardous drugs, it may become contaminated with residues or splashes that pose risks if not disposed of correctly. Collecting this contaminated equipment in designated hazardous waste containers minimizes the risk of exposure to hazardous substances for all personnel involved in waste management and disposal processes. This practice adheres to the standards outlined in USP <800>, which provides guidelines for handling hazardous drugs safely.

The other options would violate safety protocols. Cleaning and reusing PPE may not effectively remove all hazardous residues, putting workers at risk. Donating used PPE is inappropriate since it could expose others to hazardous substances. Disposing of contaminated PPE in regular trash does not comply with safety regulations and could lead to environmental contamination and health hazards. Therefore, proper disposal in hazardous waste containers is critical for ensuring safety and compliance with regulations.