What PPE is specifically required for administering hazardous drugs?

The correct answer highlights the specific personal protective equipment (PPE) necessary for safely administering hazardous drugs, particularly injectable antineoplastic medications. According to USP Chapter 800, which outlines the handling of hazardous drugs, the use of two pairs of chemotherapy gloves is mandated to minimize the risk of exposure to these potent agents. The first pair serves as the primary barrier, while the second (outer) pair adds an additional layer of protection against any possible contamination.

In conjunction with gloves, the requirement for gowns is crucial; these gowns must be made of materials that resist the permeation of hazardous drugs, ensuring that the skin and clothing are adequately protected during the administration of chemotherapy. This comprehensive approach is aimed at safeguarding healthcare workers from occupational exposure and ensuring a higher standard of safety in the handling of hazardous drugs.

Other options lack the necessary components or specificity required by the safety standards set forth in USP 800. For example, simply wearing one pair of gloves and masks does not provide the level of protection needed for handling antineoplastic agents. Likewise, only wearing a lab coat or disposable gowns and face masks does not meet the rigorous standards for protecting against hazardous drug exposure, particularly during injection procedures, where risk of spill or aerosolization is higher. Therefore, the choice