What precaution should be observed when using delivery systems for hazardous drugs?

When working with delivery systems for hazardous drugs, it is vital to avoid systems that may aerosolize or generate dust. Aerosolization can create breathable particles that pose a significant health risk to healthcare workers and patients, especially those who may have compromised immune systems or respiratory conditions. Dust generation can lead to contamination of the work environment and unintended exposure to hazardous medications.

Effective risk mitigation strategies in handling hazardous drugs require the use of containment systems that reduce the likelihood of creating aerosols or dispersing particles into the air. This practice is essential to maintaining safety standards and ensuring that exposure levels are kept within acceptable limits as outlined in documentation like USP General Chapter <800>, which focuses on handling hazardous drugs in health care settings.

The other options do not prioritize the critical issue of exposure risks associated with aerosolization and dust. While labeling and maintaining proper storage temperatures are important for safe handling of hazardous substances, the primary concern is ensuring that products do not aerosolize or generate dust to protect the health of all personnel involved.