When should a new risk assessment for hazardous drug handling be conducted?

A new risk assessment for hazardous drug handling should be conducted whenever new drugs are introduced because each hazardous drug can present different risks based on its properties, potential exposure routes, and the specific handling requirements. The introduction of new drugs may necessitate a reevaluation of existing safety protocols and procedures to ensure that all personnel involved in handling these drugs are adequately protected.

The risk assessment process should be dynamic and responsive to changes in the drug inventory, as this allows for the implementation of appropriate safety measures tailored to any newly introduced drugs. This proactive approach helps to maintain a high standard of safety and compliance within the facility.

Other options, such as conducting a risk assessment only annually or at the beginning of each calendar year, do not consider the variable nature of drug handling risks when new agents are added to the formulary. Similarly, while staff changes might warrant a review of training and protocols, they do not inherently require a risk assessment unless new drugs are introduced.