Which of the following practices is essential for handling antineoplastic hazardous drugs?

Using specialized equipment is essential for handling antineoplastic hazardous drugs because these drugs can pose significant health risks to those who come into contact with them. Specialized equipment, such as ventilated cabinets (e.g., Class II biological safety cabinets), personal protective equipment (PPE), and specific containment devices, help minimize exposure and protect healthcare workers from inhalation or dermal exposure to these hazardous compounds.

The use of specialized equipment ensures that there is effective ventilation, proper containment, and adequate shielding, which are critical for maintaining a safe working environment when handling these potent medications. This practice aligns with the guidelines set forth by USP <800>, which specifies requirements for safe handling of hazardous drugs in healthcare settings, including storage, compounding, and administration processes.